CRISPR gene-editing could result in more successful birth rates

September 27, 2017 -

By  Saqib Shah

Gene-edited human embryos are offering new insights into the earliest stages of development, and could reduce the risk of miscarriage at the outset of pregnancy. In a new study, researchers from the UK’s Francis Crick Institute used CRISPR Cas9 to block a gene (known as OCT4) in human embryos. By stopping it from functioning, the researchers saw that it no longer produced its resulting protein (also called OCT4). As a result, the human embryos ceased to attach or grow sufficiently. Their findings, published in the journal Nature, illustrate the importance of the gene in human development.

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