Building a strong, modern, globally competitive manufacturing sector is critical to expanding America’s economic prowess in the 21st century. If America is to remain a global manufacturing leader, investments in science and engineering research and workforce development must remain at the forefront of the national public policy agenda. Almost two-thirds of advanced stage research and development (R&D) is performed by U.S. manufacturers, making this sector critical to the commercialization of new technologies. In addition to supporting technological innovation and providing high-paying jobs, the manufacturing sector also provides a powerful multiplier effect on other parts of the economy, generating additional jobs in industries such as research, retail, shipping, services, and more. Furthermore, because of the need to maintain domestic capacity for the manufacturing of key products – and the need to maintain a highly skilled and creative domestic workforce to support those products – manufacturing also plays a critical role in America’s national security apparatus – making manufacturing the foundation for both a strong, globally competitive and innovative economy and a strong national defense.